受国际合作部国际合作与交流资金资助,应6163银河线路检测中心田波平教授的邀请,美国加州大学河滨分校(University of California, Riverside)统计系马舒洁副教授将于2019年6月20日—2019年6月25日来访公司,并做3场学术讲座和2次座谈,欢迎感兴趣的师生参加。 报告1:Heterogeneity and Subgroup analysis via non-convex fusion penalization 时间:2019年6月21日9:00-10:30 地点:格物楼503 摘要:Understanding treatment heterogeneity is essential to the development of precision medicine, which seeks to tailor medical treatments to subgroups of patients with similar characteristics. One of the challenges of achieving this goal is that we usually do not have a priori knowledge of the grouping information of patients with respect to treatment effect. To address this problem, we consider a heterogeneous regression model which allows the coefficients for treatment variables or the means to be subject-dependent with unknown grouping information. We develop a concave fusion penalized method for estimating the grouping structure and the subgroup-specific treatment effects. This procedure automatically divides the observations into subgroups. We develop an alternating direction method of multipliers algorithm with concave penalties to implement the proposed approach and demonstrate its convergence. We also establish the theoretical properties of our proposed estimator and determine the order requirement of the minimal difference of signals between groups in order to recover them. These results provide a sound basis for making statistical inference in subgroup analysis. Moreover, I will talk about applications of our approach to both cross-sectional data and longitudinal data settings. This talk is based on the papers Ma and Huang (2017, JASA) and Ma, Huang, Zhang and Liu (2019, IJB, revision resubmitted). 座谈1:个人科研经历与培养员工经验浅谈 时间:2019年6月21日10:30-12:00 地点:格物楼503 报告2:A robust and efficient approach to treatment effect estimation based on sparse sufficient dimension reduction 时间:2019年6月21日14:30-16:00 地点:明德楼(数学研究院)201室 摘要:A fundamental assumption used in causal inference with observational data is that treatment assignment is ignorable given measured confounding variables. This assumption of no missing confounders is plausible if a large number of baseline covariates are included in the analysis, as we often have no prior knowledge of which variables can be important confounders. Thus, estimation of treatment effects with a large number of covariates has received considerable attention in recent years. Most existing methods require specifying certain parametric models involving the outcome, treatment and confounding variables, and employ a variable selection procedure to identify confounders. However, selection of a proper set of confounders depends on correct specification of the working models. The bias due to model misspecification and incorrect selection of confounding variables can yield misleading results. In this talk, I will talk about a robust and efficient approach we have proposed for inference about the average treatment effect via a flexible modeling strategy incorporating penalized variable selection. Specifically, we consider an estimator constructed based on an efficient influence function that involves a propensity score and an outcome regression. We then propose a new sparse sufficient dimension reduction method to estimate these two functions without making restrictive parametric modeling assumptions. The proposed estimator of the average treatment effect is asymptotically normal and semi-parametrically efficient without the need for variable selection consistency. In the end, I will talk about simulation studies and a biomedical application. This talk is based on the paper Ma, Zhu, Zhang, Tsai and Carroll (2018, AoS). 报告3:Estimation and Inference in Semiparametric Quantile Factor Models 时间:2019年6月22日8:30-10:00 地点:格物楼503 摘要:In this talk, I will introduce an estimation methodology for a semiparametric quantile factor panel model. I will also talk about our proposed tools for inference that are robust to the existence of moments and to the form of weak cross-sectional dependence in the idiosyncratic error term. Specifically, we use sieve techniques to obtain preliminary estimators of the nonparametric beta functions, and use these to estimate the factor return vector at each time period. We then update the loading functions and factor returns sequentially. We derive the limiting properties of our estimated factor returns and factor loading functions under weak conditions on cross-section and temporal dependence. Lastly, I will talk about applications of our method to daily stock return data. This is a joint work with Oliver Linton and Jiti Gao. 座谈2:国内外科研环境亲身经历对比浅谈 时间:2019年6月22日10:00-11:30 地点:格物楼503 报告人简介:马舒洁,美国加州大学河滨分校统计系副教授。主要研究精准医学,因子模型,大规模数据分析,高维数据、函数型数据与非线性时间序列数据的统计推断,及其在基因与环境交互作用、环境风险评估、医学与金融数据中的应用等。已在Annals of Statistics、Journal of the American Statistical Association、Journal of Econometrics、Statistics in Medicine、Bernoulli、Statistica Sinica等期刊上发表论文30余篇,并在国际上已累计做学术会议报告超过30次。现任Journal of Business & Economic Statistics、Computational Statistics and Data Analysis、The American Statistician、Statistica Sinica、Journal of Statistical Planning and Inference期刊的副主编。 |